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Our immune system is remembering COVID-19 and fighting against its variants, study shows

Two years after the COVID-19 pandemic, researchers want to know how well humanity is coping with the onslaught of the new. variant.

Figuring out whether our immune system is up to the task, however, will require a mathematical feat. So researchers turned to sophisticated computer models for answers.

Think of the coronavirus as one side of the zipper and your immune system on the other.

If every tooth fits and you can pull it up, your immune system can stop the invaders – but if the teeth don’t fit and the sides can’t slide against each other, your immune system can’t. you can’t keep up with the molecular virus that invades parts.

We’re not talking about antibodies, we’re talking about T cells.

“That side of the immune system is significantly safer and significantly stronger,” said Dr Eric Vail, Director of Molecular Pathology at Cedars-Sinai.

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Zippers are a simple analog of HLA types found on human T cells and parts of antigens found on viruses. We need our HLAs to recognize the virus so we can protect ourselves.

“Can your body recognize the virus when it enters? (Will) markers on your immune cells … be able to see it?”

Vail said a new report in PLOS . Computational Biology is assured. Although researchers have identified variants capable of escaping our body’s immune response, there’s good news. Scientists detect failure only 15% of the time.

“We still have a large functional reserve left,” he said. “They tested it with 90% of the world’s population. But in that 90%, the worst thing that happened was a 15% drop.”

Research shows that over the past two years most people’s T cells have developed a memory that will function when faced with different variations. Exposure is part of the reason, but Vail says most of the credit goes to vaccines.

“Basically, it trains your immune system. It trains it how to recognize and see the pathogen and how to react against it in a way that protects you,” Vail said.

His advice is to get vaccinated and stay healthy. The more training, the better.

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https://abc13.com/covid-variants-immune-system-vaccine-virus/11575669/ Our immune system is remembering COVID-19 and fighting against its variants, study shows

Dais Johnston

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