Obesity could be cured without diet or exercise by turning off ‘hunger hormone’ as radical trial launched

OBESITY can be cured without diet or exercise with a radical trial launched to eliminate the so-called “hunger hormone”.

The trial was set up to investigate a process that could cut the desire to overeat and weight loss in just 40 minutes.

People with obesity can turn off "hunger hormone" through a procedure called vascular embolization


People with obesity can turn off their “hunger hormone” through a procedure called vascular embolizationCredit: Getty Images

And the process will cost NHS £1,500 – a quarter of the price of conventional fat reduction surgery.

One trial, led by Ahmed R. Ahmed, a liposuction surgeon at St Mary’s Hospital in London, will see nearly 80 volunteers undergo a procedure known as vascular embolization and turn off ghrelin, which is nicknamed the ‘hunger hormone’.

Due to costs and logistics, the NHS performs 6,000 rigorous procedures such as waistbands, bypasses and sleeves each year, resulting in long waiting list.

Talk to MailOnlineMr. Ahmed said that if vascular embolization becomes routine, patients can be discharged in two hours.

“You can be hungry and come out not hungry,” he says.

The doctor says the method’s fast speed and low cost will open up obesity treatments for more people, but says its effectiveness needs to be proven first.

“We really need to know that the intervention itself worked, and it wasn’t just a placebo effect,” he added.

The surgery, performed under local anesthesia, involves making a small cut in the groin or wrist and threading a hollow wire through the blood vessels.

The microscopic particles are then deposited in an artery serving the upper stomach, or artery, which causes a blockage and thus reduces ghrelin production.

Small-scale studies have found that obese patients lose almost 10% of their weight on average after the procedure, although some lose more.

As weight loss will significantly improve health, reverse type 2 diabetes and reduce the risk of cardiovascular disease.

Mr. Ahmed’s team is recruiting 76 obese volunteers, each with a body mass index between 35 and 50. Half will receive blocker beads, the rest will receive a placebo saline solution and all They will be followed up for a year.

The trial has received £1.2 million from the NHS’s National Institutes of Health and is supported by Imperial College London.

While no patients have been treated in the UK yet, around 25 have been treated in the US. Among them was local nurse Kirsten Kerfoot, 32, who lost six and a half stones.

The mother of one child, who is 5ft 11in tall and currently weighs 15 stone, said: “I can’t remember a time in my life when I wasn’t overweight or obese.

“I used to see Chinese food commercials on TV and thought, ‘I want it!’ That thought would stay in my mind for days.It was my experience all my life – with food clinging to me.

“Thanks to this procedure, I don’t like to eat like that anymore. It’s like no food processing.”

Dr Clifford Weiss of Johns Hopkins University School of Medicine in Baltimore, Maryland, who is leading a parallel trial of 64 US patients, said: “The goal here is to make patients healthier in a way that’s healthy. as minimally invasive as possible.”

The treatment has been welcomed by Tam Fry, of the National Obesity Forum, who said the NHS must look at cheaper, faster alternatives to bariatric surgery, adding: “Obesity is now It’s a big deal, we have to think through it.”

The NHS performs 6,000 ban procedures a year, resulting in long waiting lists


The NHS performs 6,000 ban procedures a year, resulting in long waiting listsCredit: Getty Images Obesity could be cured without diet or exercise by turning off ‘hunger hormone’ as radical trial launched

Tom Vazquez

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