Nobel Prize in Chemistry to Bertozzi, Meldal, Sharpless for attaching molecules

This year’s Nobel Prize in Chemistry was awarded equally to Carolyn R. Bertozzi, Morten Meldal and K. Barry Sharpless for developing a method of “sticking molecules together” that can be used to design drugs.

Their work, known as click chemistry and bioorthogonal reactions, is used to make cancer drugs, map DNA, and create materials tailored for a specific purpose.

Hans Ellegren, Secretary General of the Royal Swedish Academy of Sciences, announced the winners on Wednesday at the Karolinska Institute in Stockholm, Sweden.

Bertozzi is based at Stanford University in California, Meldal at the University of Copenhagen, Denmark, and Sharpless is affiliated with Scripps Research, California.

Sharpless received a Nobel Prize in 2001. He is the fifth person to receive the award twice.

Members of the Nobel Committee for Chemistry (bottom L-R) Chair Professor of Theoretical Chemistry Johan Aqvist, Secretary General of the Royal Swedish Academy of Sciences Hans Ellegren and Professor of Chemistry Olof Ramstrom speak at a press conference to announce the winners (on display) of the 2022 Nobel Prize in Chemistry at the Royal Swedish Academy of Sciences in Stockholm on October 5, 2022.
Winners’ work will be used to make cancer drugs, map DNA and create materials tailored for a specific purpose.
AFP via Getty Images

Last year, the prize went to scientists Benjamin List and David WC MacMillan for discovering a sophisticated and greener way of building molecules that the Nobel panel said is “already bringing great benefits to mankind.”

A week of Nobel Prize announcements began on Monday when Swedish scientist Svante Paabo received the Medicine Prize for unlocking the mysteries of Neanderthal DNA, which provided important insights into our immune system.

An advertisement shows 2022 Nobel Prize in Chemistry winners, United States' Carolyn Bertozzi (L) and Barry Sharpless (R), along with Denmark's Morten Meldal (C) during a news conference at the Royal Swedish Academy of Sciences in Stockholm April 24, 2022 October.  5, 2022.
K. Barry Sharpless is the fifth person to receive a Nobel Prize twice.
AFP via Getty Images

Three scientists jointly won the prize in physics on Tuesday. Frenchman Alain Aspect, American John F. Clauser and Austrian Anton Zeilinger had shown that tiny particles can remain connected to each other even when separated, a phenomenon known as quantum entanglement and used in specialized computers and encryption of information can be used.

The awards will continue with literature on Thursday. The 2022 Nobel Peace Prize will be announced on Friday and the Economics Prize on Monday.

The prizes are worth 10 million Swedish kronor (almost US$900,000) and will be presented on December 10th. The money comes from a legacy left by the prize’s creator, Swedish inventor Alfred Nobel, in 1895.

https://nypost.com/2022/10/05/nobel-chemistry-prize-awarded-to-bertozzi-meldal-sharpless-for-attaching-molecules/ Nobel Prize in Chemistry to Bertozzi, Meldal, Sharpless for attaching molecules

JACLYN DIAZ

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