Scientists at the Austrian Institute of Molecular Biotechnology academy of Services believes it has discovered a “promising avenue” for a new type of birth control pill that can only be taken when needed.
This will also make birth control pills more widely available because some women, such as breast cancer survivors, cannot receive hormone treatment.
In the study, published in nature In the journal Nature, scientists used human blastoids – structures of human tissue that mimic early human embryos – to look at the key stages an embryo goes through during early development.
During the first week of fertilization, the human embryo forms a sphere of cells, called a blastocyst, that nests in the uterine wall.
To reproduce this, blastoids were cultured for up to 13 days, at which point they contained 300 cells.
By mimicking these early stages, researchers have discovered molecules that could be used to develop a non-hormonal contraceptive.
Nicolas Rivron, one of the study’s authors, said the team hopes these molecules can “make family planning easier, more convenient and more adaptive to current social challenges.” now on”.
The researchers also discovered a new effect of an existing molecule, called lysophosphatidic acid.
According to the study, under this new effect, the molecule can improve the self-organization of stem cells and thus, promote embryogenesis during IVF treatment.
“We hope we can use such molecules to improve the quantity and quality of IVF embryos, and the chances of pregnancy,” says Rivron.
“Our goal is to empower women by allowing them to take better control of their fertility, whether they want to avoid pregnancy or increase their chances of having a baby.”
“By using blastoid, we speed up research and make it more ethical. It is clear that scientific and biomedical knowledge will skyrocket with practical in vitro models for early pregnancy.”
https://www.independent.co.uk/life-style/women/embryo-research-contraceptive-pill-ivf-b1968635.html New embryo research could improve IVF rates and pave the way for hormone-free pills