Breakthrough infection may induce ‘super immunity’ to COVID-19, study suggests

A study from the Oregon Health and Science University found that antibodies produced by vaccination and a breakthrough were more effective at fighting the virus that causes COVID-19. (Photo by Spencer Platt / Getty Images)

(NEXSTAR) – Researchers at Oregon Health and Science University say they have found evidence that breakthrough infections induce “super immunity” to the virus that causes COVID-19 .

“You can’t get a better immune response than this,” said senior author Fikadu Tafesse, PhD, an assistant professor at OHSU School of Medicine, in a statement. New information posted. “These vaccines are very effective against severe disease. Our study suggests that individuals who are immunized and then exposed to a disruptive infection have superimmunity.”

Specifically, Tafesse and his team found that antibodies in the blood of a vaccinated person who experienced a breakthrough can be 1,000% more effective than antibodies found in some people. fully immunized not infected.

They also believe that antibodies generated from the breakout cases are “likely” more effective against the SARS-CoV-2 variants, although the researchers did not specifically test the effectiveness of the virus. them for the omicron variation.

However, the study only examined blood samples from 26 people with the mutation – all OHSU employees and all fully vaccinated. with the Pfizer vaccine. However, when compared with a sample of 26 vaccinated staff members who had not experienced mutations, antibodies from the infected group were detected in greater numbers and were “more effective in neutralizing live virus”.

Study co-author Marcel Curlin, MD, said the results could indicate a “final game over” for the pandemic.

“That doesn’t mean we’re at the end of the pandemic, but it does indicate where we might land: Once you’ve been vaccinated and then exposed to the virus, you can will be quite healthy,” said Curlin.

Meanwhile, health officials continue to encourage vaccination and booster shots as the best defense against COVID-19, especially in the face of the expected dominance of the variant. omicron.

Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, said on Thursday that booster shots are especially important to “regenerate” protection among people who are already fully immunized. enough, even if they may not prevent omicron infection.

“It may not provide much protection against infection, but it will a long way to protection from serious illness,” he said Thursday at an American Chamber of Commerce Foundation event.

Fauci also said the omicron will likely become the dominant variant within “a few weeks,” but stressed that unvaccinated people are still very vulnerable to the delta variant, which is now resurgent in the US.

https://kfor.com/news/breakthrough-infections-may-create-super-immunity-to-covid-19-study-suggests/ Breakthrough infection may induce ‘super immunity’ to COVID-19, study suggests


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