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I am the first patient to receive a pig heart transplant

The first patient to receive a pig heart transplant called the unique medical method “shot in the dark” that could save his life.

A pig heart was transplanted to 57-year-old David Bennett on Friday at the University of Maryland Medical Center in Baltimore, Maryland.

Dr Bartley Griffith, left, poses for a selfie with patient David Bennett

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Dr Bartley Griffith, left, poses for a selfie with patient David BennettCredit: AP

The experimental surgery – which took seven hours to complete – led doctors at the medical center to confirm the procedure showed that a heart from a genetically modified animal could function in the human body without rejection. right away.

Bennett said in a statement, obtained by Related press the day before surgery: “It died or it was transplanted.

“I want to live. I know it’s a shot in the dark, but it’s my last choice.”

His son, David Bennett Jr, told the news agency his father was not eligible for a human heart transplant and that it was his only option for a chance at life – although it is not guaranteed to help. .

On Monday, three days after surgery, doctors said Bennett was breathing on his own while connected to a heart-lung machine.

Dr Muhammad Mohiuddin, scientific director of the University of Maryland’s animal-to-human transplant program, said: ‘If this works, there will be an endless supply of these organs for the suffering patients”.

The experimental surgery comes as the organ shortage crisis unfolds.

It also follows previous unsuccessful attempts at xenotransplant transplantation, described by FDA is “any procedure involving the transplantation, transplantation, or infusion into the recipient of (a) living cells, tissues or organs from an animal source other than human …

“Or (b) human body fluids, cells, tissues or organs that have been exposed ex vivo to non-living animal cells, tissues or organs.”

Back in 1984, a dying baby named Fae lived 21 days with a baboon heart until it broke.

In Bennett’s case, however, surgeons in Maryland used a pig heart that had undergone gene editing to remove a sugar in its cells, which is known for its ability organ rejection.

The surgery was approved by the FDA under an “charity use” emergency permit, because Bennett’s condition was life-threatening and no other options could help save him.

Dr Robert Montgomery said in a statement: “This is a truly remarkable breakthrough.

“As a heart transplant recipient with an inherited heart disorder myself, I am delighted by this news and hope it brings back my family and other patients, whose lives will ultimately be saved. thanks to this breakthrough.”

Dr Bartley Griffith, who performed the surgery and has previously transplanted pig hearts into dozens of baboons, said: “We learn a lot every day with this gentleman.

“And so far, we’re happy with our decision to move forward. And so is he: The big smile on his face today.”

According to Griffith, Bennett is not eligible for a human heart transplant or a heart pump because he has heart failure and an irregular heartbeat.

Bennett’s son told AP News his father previously had pig heart valve surgery about 10 years ago, something that has been used successfully in humans for decades.

“He recognized the importance of what was done and he really recognized the importance of it,” said Bennett Jr. speak.

Meanwhile, Dr. Muhammad M. Mohiuddin, UMSOM’s Professor of Surgery, said: “This is the culmination of years of very complex research to hone this technique in animals whose survival times have been more than nine months.

“The FDA used our data and data on the laboratory pig to enable transplantation in a patient with end-stage heart disease who had no other treatment options.

“The successful procedure provided valuable information to help the medical community improve this potentially life-saving approach in future patients.”

A pig heart transplanted into a 57-year-old man at the University of Maryland Medical Center in Baltimore, Maryland

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A pig heart transplanted into a 57-year-old man at the University of Maryland Medical Center in Baltimore, MarylandCredit: EPA
The activity took seven hours to complete

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The activity took seven hours to completeCredit: AFP

https://www.thesun.co.uk/tech/17282952/first-human-patient-pig-heart-transplant/ I am the first patient to receive a pig heart transplant

Caroline Bleakley

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