The crash was reported just before 5 a.m. on southbound I-45 in Scarsdale. Police confirmed that at least one person died.
Video from the scene shows a car flipped on the freeway. Two other cars were stopped at the scene, although it was unclear how many cars were involved in the accident.
All southbound lanes were closed while crews continued to investigate the accident site.
What exactly led to the crash and how many people were injured was unclear.
Motorists can take Highway 3 as an alternate route.
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https://abc13.com/fatal-crash-houston-traffic-gulf-freeway-deadly-wreck/11792103/ Houston traffic: Car overturns in fatal accident on Gulf Freeway in Scarsdale