Everything you need to know about the HPV Vaccine and Cervical Cancer

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Since the first human papillomavirus (HPV) vaccine was approved by the FDA in 2006, there has been quite a bit of controversy surrounding this vaccine, which protects against related STDs. Cancers can be deadly.

However, new research in the UK offers compelling evidence that the vaccine works: The study was published November 3 in the medical journal Fingertips, noticed that Great Britain National Health Service (NHS) immunization program There was an 87% reduction in cervical cancer cases among women who received the HPV vaccine between the ages of 12 and 13.

However, “as age increases, the effectiveness of vaccines decreases,” Dr. Darren P. Mareiniss, MD, an assistant professor of emergency medicine at the Sidney Kimmel College of Medicine at Thomas Jefferson University in Philadelphia, who was not involved in the study, explains. “For the 14 to 16 group, the cancer risk decreased by 62%, and for the 16 to 18 group, the reduction was only 34%.”

Dr. Sangini Sheth, MD, MPH, Yale Gynecologist and associate professor of obstetrics and gynecology and reproductive sciences at Yale Medical School, adds that the population-based study from the UK is the first of its kind. “Given that cervical cancer takes many years to develop, previous studies have used surrogate outcomes (eg, genital warts, cervical precancerous conditions) to evaluate,” she says. effectiveness of the HPV vaccine.

“Now that the vaccine has been available in many countries for more than a decade, we are starting to look at studies like this one to look at the effects of the HPV vaccine on cervical cancer. cancer.”

Still curious about the HPV vaccine? Here are six things to know about it.

There are three types of HPV vaccines, but only one is used in the United States

Follow Centers for Disease Control and Prevention, there are three types of HPV Vaccine: Gardasil® 9, Gardasil®, and Cervarix®. While all have been shown to be safe and effective in clinical trials, as of late 2016, Gardasil® 9 is the only one administered in the United States.

Related: Does HPV go away?

It is extremely effective in protecting against HPV-related cancers

In addition to cervical cancer, HPV has been linked to cancers of the throat, cervix, vulva, vagina, penis, and anus. American Cancer Society confirmed that the HPV vaccine provides almost 100% protection against infections and pre-cancers caused by certain types of HPV. They explain on their website: “Vaccinating boys and girls between the ages of 9 and 12 can prevent more than 90% of HPV cancers when they get older.

Dr Sheth adds: “The vaccine is very effective in protecting against the nine strains of HPV known to cause 90% of genital warts and 85% of cervical cancers. The vaccine protects against other HPV-related cancers, including cancers of the oropharynx, anus, penis, vulva, and vagina.

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It does not cause fertility problems

Much learn found no link between the HPV vaccine and infertility. However, the CDC points out that not getting vaccinated makes people more susceptible to HPV-related cancers and pre-cancers, which may require treatment, hysterectomy (for women), chemotherapy or radiation, limiting their ability to have children. In addition, treating cervical pre-cancers can potentially put women at risk for cervical problems, sometimes leading to premature birth.

Related: Why can’t I get pregnant?

You will need two or three shots

The HPV vaccine requires two or maybe three shots, according to Dr. Mareiniss. “For ages 9 to 14, two shots are needed, the second 6 to 12 months after the first,” he explains. Vaccinated people between the ages of 15 and 45 and immunosuppressed children need three shots, a second one to two months after the initial vaccination and another at six months.

It’s more effective when it’s administered earlier

The HPV vaccine is approved for use in children under nine years of age. However, CDC recommends vaccine for girls aged 11 to 12 years. “The best time to get vaccinated is 11-12 years old or earlier. Basically, the sooner the better,” says Dr. Why? HPV is the most common cause of cervical cancer and is sexually transmitted, often occurring early in life life during the first few times of sex, he explained. “As a result, the vaccine is most effective prior to sexual activity.”

The Lancet study clearly demonstrated this, when vaccinated girls aged 12 to 13 had an 87% reduction in their risk of cervical cancer, while those who waited until 14 to 16 had only a 62% reduction and from 16 to 18 years old decreased only 34%.

Dr Sheth adds that anyone 26 and older should get the vaccine if they didn’t get it as a child or teen, “and for those 27-45 years old, some people may benefit from the vaccine. and they should ask their healthcare provider about it.”

Side effects are minimal

Dr. Sheth asserts that the HPV vaccine is extremely safe, with more than 15 years of data supporting it. Each data is collected by Immunization Action Coalition, in clinical trials with more than 15,000 subjects, the most common adverse reaction was pain at the injection site (70%), followed by redness or swelling at the injection site (30%) Systemic reactions were very rare. , only 2-15% reported fever, headache or fatigue.

Next: 25 cancer facts that can help save lives

The source

https://parade.com/1292112/leah-groth/hpv-vaccine-cervical-cancer-study/ Everything you need to know about the HPV Vaccine and Cervical Cancer

Caroline Bleakley

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